This was the day American women came back to earth at the French Open. Three of them — the three not named Serena Williams — lost Monday, meaning only Williams remains after four made it to the fourth round.

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PARIS — This was the day American women came back to earth at the French Open.

Three of them — the three not named Serena Williams — lost Monday, meaning only Williams remains after 15 American women started the tournament in singles play and four made it to the fourth round. It was the first time since the 2004 U.S. Open that four American women had reached the fourth round of a Grand Slam tennis tournament.

Sloane Stephens, seeded 17th, lost 6-4, 6-3 to defending champion Maria Sharapova of Russia.

Unseeded Jamie Hampton was routed 6-0, 6-2 by No. 18 Jelena Jankovic of Serbia and unseeded Bethanie Mattek-Sands lost to No. 12 Maria Kirilenko of Russia 7-5, 6-4.

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Stephens said she was not disappointed after the loss to Sharapova, adding that after a stressful couple of months — which included a controversy over remarks she made about Williams in a series of interviews — it felt good to play well again.

“Overall, I’ve done pretty well,” the 20-year-old Stephens said. “Not to have played that well coming into the clay-court season and to get a good amount of matches in and get some confidence, I think, is good.”

For Mattek-Sands, the French Open represented a strong return to competitiveness after a spell of injuries.

“I’m really pumped, actually,” she said. “It was a nice breakthrough. I had one of the best ones of my career. I’m feeling good. Feeling confident with my game still, even after the loss. You know, that didn’t go anywhere. I’m excited for the next tournament, and I think I want to keep upping this momentum.”

The top-ranked Williams, meanwhile, advanced to the quarterfinals by winning Sunday and will play Svetlana Kuznetsova of Russia on Tuesday.

In fourth-round men’s matches, No. 1 Novak Djokovic of Serbia beat No. 16 Philipp Kohlschreiber of Germany 4-6, 6-3, 6-4, 6-4 and seven-time champion Rafael Nadal of Spain beat No. 13 Kei Nishikori of Japan 6-4, 6-1, 6-3.

Djokovic and Nadal stayed on course for a potential semifinal meeting.

No. 12 Tommy Haas, a 35-year-old from Germany, beat No. 29 Mikhail Youzhny of Russia 6-1, 6-1, 6-3 to become the oldest French Open men’s quarterfinalist since 39-year-old Istvan Gulyas in 1971.

Haas has had serious injuries and operations, including to his right shoulder and hip, and he missed more than a full season.

“Who would have thought two years ago I’d be in this position today?” Haas asked. “I wouldn’t have.”

By the second set, Youzhny was so out of sorts he destroyed a racket by slamming it nine times against his sideline seat.