Scratch snaps his streak of playing in 110 consecutive games.

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Robinson Cano’s name has been such a given on the Mariners’ lineup card since he arrived that the one for Thursday’s game against the Cleveland Indians required a double-take, just to be sure.

Cano didn’t start the series opener against Cleveland with “flu-like symptoms,” Seattle manager Lloyd McClendon said, replaced by Brad Miller at second base and by Nelson Cruz in the three-hole in the batting order. Cano, however, pinch-hit in the ninth inning and flew out to right.

The last time Cano missed an entire game was last July 20, a 6-5 loss to the Angels in Anaheim. Cano played in all but five of Seattle’s games in 2014 – that Angels loss and four straight games at the end of May. His PH appearance extended his playing streak to111 consecutive games.

“He’s sick,” McClendon said before the game, “ … dehydrated, taking an IV. I’m not sure how much fluid he’s gotten back in, but he’s dehydrated. He’s lost a few pounds.”

Cano was hitting .253 with one home run and 13 RBI in Seattle’s first 46 games. He, Nelson Cruz and Kyle Seager — Seattle’s usual 3-4-5 hitters — had combined to hit .297 with 15 home runs and 40 RBI in May entering Thursday.

Iwakuma plays catch

Mariners starting pitcher Hisashi Iwakuma played catch Thursday for the first time since landing on the 15-day disabled list with a lat strain on April 24, but a possible return is still at least a week away, McClendon said.

“He’ll continue to progress with his rehab, and we’ll see how it goes,” McClendon said. “Obviously, he’s getting to the point where he feels good enough to get on the mound. I’ll be surprised (if he returns) in the next seven or eight days. The discomfort and the inflammation has dissipated to the point where he can get out and continue his rehab.”

Iwakuma racked up a 6.61 ERA in three starts prior to the injury, allowing 13 runs on 20 hits and three walks in less than 17 innings of work.

The third-place finisher in the 2013 American Cy Young Award voting went 15-9 with a 3.52 ERA in 28 starts last season.

M’s return home

The last time the Mariners set foot on the plush blue carpeting of their Safeco Field clubhouse, they were on the back end of a dispiriting homestand, three games under .500 and with a long trip hanging over their heads.

They returned home winners of six out of nine and with a record evenly split at 23-23.

Thursday’s four-game series opener was the first of 11 straight home games for the Mariners, their longest such stretch of the season. This is just Seattle’s second homestand of 11-plus games dating to 2005.

Note

• Cleveland first baseman Brandon Moss’ solo home run in the second inning of Thursday’s game was the first Seattle starter James Paxton had allowed to a left-handed batter in his career.