The M’s didn’t get to the Angels’ new two-way star until the seventh inning, but by then they were already down six runs as Felix Hernandez gets bitten by two homers and some bad luck.

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At some point, the hurt and disappointment of seeing Shohei Ohtani in an Angels uniform will fade from the minds of the Mariners and their fans. Though the resentment might still remain for years.

After facing him as a hitter and a pitcher for the first time in this weekend three-game series, the daydream of “what could have been” can be replaced by the dread of “what will be” in facing him more than a dozen times in a season in either capacity.

On a beautiful Sunday afternoon at Safeco Field, the Mariners saw the pitcher they’d hoped to add to their rotation this offseason carving up their powerful lineup with precision, throwing 97-mph fastballs on the corners with diving split-fingers and exploding sliders for swings and misses. Everything the Mariners hoped he would be for them, he did against them in an 8-2 loss to the Angels.

TUESDAY

Mariners @ Toronto, 4:07 p.m., ROOT Sports

It was a disappointing end to the homestand and the series for the Mariners, particularly after Saturday night’s ridiculous come-from-behind win in extra innings.

“Not quite as fun as last night,” M’s manager Scott Servais said. “Disappointing not to win the series. We are going to play them a lot this year. We expect a lot of close games. It just didn’t go our way this weekend.”

For the first time since facing the Astros in April, the Mariners lost a series. They had won four in a row.

Ohtani didn’t allow a run in his first six innings and struck out six batters. Seattle mustered two singles from Kyle Seager, a walk from Ryon Healy and curveball off the rear end of Nelson Cruz for base runners.

“The fastball has got velocity,” Servais said. “There were stretches where he commanded it better than others. The secondary pitches are real. The curveball, the slider and splitfinger all have depth. They are hard. He’s very poised. He gave us chances that we didn’t turn into hits or big hits at all.”

It’s never enjoyable for hitters to see a pitcher for the first time, but it’s magnified with pitchers such as Ohtani that possess such velocity and movement.

“Whenever you have someone that throws that electric of stuff — different pitches moving all different sorts of ways — the second time and third time around is always better,” Healy said. “We are going to have to use that, definitely doing some more studying on the video we had out there today.”

It won’t make it easier, but it will make it familiar.

“It’s about giving yourself more knowledge and understanding of a game plan and what things look like,” Healy said. “Giving yourself the best opportunity.”

Healy had the biggest hit of the game off Ohtani. In the seventh inning, following a Mitch Haniger single, Healy hammered a 3-2 slider down in the zone over the wall in left field for a two-run homer.

“You are really just hunting mistakes,” he said. “Fortunately, I got one there and didn’t miss it.”

Ohtani walked Mike Zunino and was lifted from the game.

“I wasn’t happy with how I ended the game, giving up the two runs and a walk,” Ohtani said through his interpreter. “I’ve got to work on that. I was really frustrated with myself.”

Healy’s homer might have been a game-changer for the Mariners had the Angels not thrown up a four-run sixth inning for a 6-0 lead.

Seattle starter Felix Hernandez maneuvered his way through five innings without great command or stuff — an increasing trend — and allowed just two runs on a pair of solo homers in the second inning to Zach Cozart and Chris Young. Hernandez has allowed homers in all but two of his starts this season.

“I just need to keep the ball in the ballpark, that’s what I need to do,” he said. “From now on, that’s my goal.”

But the homers only produced two runs for the Angels. A Hernandez strikeout led to four runs in the sixth.

Wait, a strikeout?

Indeed, Hernandez retired the first two batters of the sixth with ease and appeared destined for a 1-2-3 inning. Up 1-2 in the count to Young, Hernandez uncorked a biting curveball that Young flailed at. The pitch was well in front of the plate and Zunino’s attempt to backhand it failed. The ball bounced to the screen and Young hustled to first.

Hernandez never recovered. Rene Rivera, the No. 9 hitter, doubled to right-center to score Young. A walk to Ian Kinsler ended Hernandez’s outing. But the runners on base were his and they scored moments later when Mike Trout crushed a 1-0 pitch from reliever Chasen Bradford for a three-run homer and a 6-0 lead.

The possibility of allowing zero runs went to four runs allowed all because of one curveball in the dirt.

“That was the ballgame,” Servais said. “We made a lot of mistakes against him and you can’t make mistakes to Mike Trout. He was in the middle of everything in this series.”

If Young is out, then Healy’s homer ties the score at 2-2 and the Mariners play the remaining innings against a shaky Angels bullpen differently.

Seattle wasn’t without other chances against Ohtani. In the bottom of the fifth, Ben Gamel was thrown out at third by Trout to end the inning. Gamel was trying to go first to third on a single to center by Dee Gordon. He was initially called safe, but replay overturned the call as his foot lifted off the base momentarily on his slide while the tag was still being applied.

A four-run lead isn’t impossible to overcome for Seattle. They had runners on first and second with two outs in the seventh after Ohtani left, but Gordon grounded into the first of two double plays in the game that killed Mariners rallies.