Ichiro played in the field in the top of the first, but was pinch hit for in the bottom of the first.

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PEORIA, Ariz. — It was the baritone voice of the public address announcer at Peoria Stadium that notified everyone of the unexpected change to start the bottom of the first inning.

“Now pinch hitting for the Mariners in place of Ichiro … Number, 57, John Andreoli,” the voice boomed over the speakers.

Wait, a pinch hitter for Ichiro in the first at-bat of the game?

Did something happen from the time Ichiro stood in left field, watching starter James Paxton strike out the side in the top of the first to when he ran in from his position to the dugoout at the end of the inning?

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Well, apparently his right calf had tightened up. And the Mariners, with a list of injured players longer than a 4 p.m. buffet line in Peoria, decided not to take any chances and removed him from the game.

“He just noticed it right away and just wanted to come out,” manager Scott Servais said. “Just precautionary.”

In the top of the fourth inning, Jean Segura was pulled from the game with right hamstring tightness. In the bottom of the third, Segura sprinted from first to third on a single from Mitch Haniger. After the inning ended, he was replaced in the lineup by Danny Muno.

“His hamstring tightened up,” Servais said. “No big issue.”

They are the 1oth and 11th players on the Mariners’ 40-man roster to deal with some sort of known injury issue. Ichiro’s seems the most minor while Segura dealt with hamstring issues early last season.

“Don’t expect those guys to be out long,” Servais said. “We’ll know more tomorrow. It’s just where we are at in spring training. Like I said, it’s the heightened awareness of what’s happened around here the last few days, those guys felt something and decided to come out.”

Mariners 40-man roster injury list

Ryon Healy, 1B — right hand surgery

  • Update: First on-field batting practice on Wednesday. Could play in a Cactus League game by this weekend.


Erasmo Ramirez, RHP — right latissimus dorsi strain

  • Update: Playing catch on flat ground. Hasn’t begun long tossing yet. The hope is he can make it back by second week in April.


Ben Gamel, LF — oblique strain

  • Update: Shutdown from baseball activities. Likely to miss the first 2-3 weeks of the regular season.


Felix Hernandez, RHP — right forearm contusion

  • Update: Threw a 25-pitch bullpen on Tuesday. He will throw another bullpen on Friday and then a Cactus League start likely Monday or Tuesday.


Nick Rumbelow, RHP — right shoulder discomfort

  • Update: None


Marco Gonzales, LHP — right hand contusion

  • Update: Gonzales will throw a bullpen on Thursday, but likely won’t be able to catch the ball when the catcher throws it back. He believes he’ll make his scheduled start on Saturday.


Robinson Cano, 2B — left hamstring strain

  • Update: The Grade 1 strain is minor. He will likely return to games by the middle of next week.


Nelson Cruz, DH — right quad strain

  • Update: Also a Grade 1 strain. Cruz plans to take 2-3 days off from baseball activities and return to game action next week.


Andrew Romine, IF/OF — right shoulder partial subluxation

  • Update: Felt the shoulder partially come out of socket. He’ll take 2-3 days off and return to games by next week.


Ichiro, RF — right calf tightness

  • Update: Left Wednesday night’s game in the first inning. He played in the field for the top of the inning and then was pinch-hit for.


Jean Segura, SS — right hamstring tightness

  • Update: Exited Wednesday’s game in the top of the fourth after going first to third in bottom of the third on a single. Dealt with hamstring issues early last season as well.