A series of raids in the Seattle area targeted a drug-trafficking ring with ties to California and Mexico, according to the U.S. Attorney's Office in Seattle.

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Seventeen people have been arrested and more than 50 pounds of methamphetamine, cocaine and heroin was seized during a series of raids in the Seattle area that targeted an international drug-trafficking ring, according to the U.S. Attorney’s Office.

The arrests culminate an 18-month investigation involving court-authorized wiretaps and the surveillance of members of the ring that authorities say have ties to California and Mexico. Some of the defendants made their initial appearances Wednesday in U.S. District Court in Seattle, where all pleaded not guilty.

In raids launched Wednesday, law-enforcement officers served search warrants on 17 homes, three storage facilities and more than a dozen vehicles in Seattle, Everett, Auburn, Bellevue, SeaTac, Tukwila, Renton, Kent and Port Orchard, the U.S. Attorney’s Office said. Officers seized 29 pounds of meth, more than 18 pounds of heroin, six pounds of cocaine, approximately $178,000 in cash and 16 firearms.

A total of 22 people have been charged with conspiracy to distribute controlled substances, and some have been charged with conspiracy to commit money laundering, according to the U.S. Attorney’s Office.

Because of the quantities of drugs involved, some of the defendants face mandatory minimum sentences of 10 years in prison if convicted, the attorney’s office said.