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Andile Madondile, 38, of Cape Town’s Khayelitsha township, was diagnosed with HIV in 2004.

“I thought I was going to die,” he said.

Madondile turned to antiretroviral drugs as a last resort, after traditional healers weren’t able to provide relief. A few months later, his health significantly improved and Madondile became a “changed man.”

Today, he works as an HIV activist and is educating and recruiting his neighbors to sign up for a clinical trial led, in part, by Fred Hutchinson Cancer Research Center.

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His HIV-negative wife, Sithembele, describes their life as happy. They have three HIV-negative children together.

Watch Andile’s story above, and read the story by Nina Shapiro: ‘We have only one shot’: The Hutch’s quest to wipe out AIDS in South Africa.