Marketed in marijuana stores and online under names such as Mojo, Black Mamba and Annihilation, Spice is said to mimic the high produced by marijuana.

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SAN DIEGO — Ten people overdosed Sunday afternoon in downtown San Diego after smoking the synthetic drug Spice, police said.

Five adults and five juveniles suffered “mild to serious symptoms” after smoking the drug, police said. Some were unconscious, others were vomiting. Several were taken to emergency rooms.

The drug may have been sold in black packages with blue dragons on the side, police said.

Police are attempting to track down all victims, witnesses and those selling the drug. Victims ranged in age from 13 to 28, according to the San Diego Fire & Rescue Department.

Marketed in marijuana stores and online under names such as Mojo, Black Mamba and Annihilation, Spice is said to mimic the high produced by marijuana. But authorities have warned of the health dangers of the drug that mixes herbs and chemicals.

The Drug Enforcement Agency has begun a nationwide crackdown on Spice.