Read about medical advances and research in Seattle and worldwide. Topics include treatments; surgery; diseases such as Zika; studies of the human brain, heart and cancer; mental health; drugs and vaccinations; and Medicare, the Veterans Administration (VA) and the Affordable Care Act, aka Obamacare. Institutions include the Hutch, UW Medicine, Harborview, Virginia Mason, Group Health and Swedish.

High-profile talks to avert landmark opioid trial break down

CLEVELAND — An 11th-hour effort to settle landmark opioid litigation collapsed Friday night after a full-day of unusual face-to-face negotiations, with the three main groups still far apart on key issues. Summoned to the federal courthouse here by U.S. District Court Judge Dan Aaron Polster, state attorneys general, corporate executives and lawyers for 2,400 cities...

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