The actor's estate centers on a 10,000-square-foot main house, and also includes guest and pool houses, vegetable gardens and a swimming pool and spa.

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Actor Rob Lowe and wife Sheryl, a jewelry designer, are preparing for the next chapter in their empty-nest lives. The couple, whose two sons both left for college in recent years, have listed their estate in Montecito, California, for $47 million.

“With our boys now out of the house, we’re looking forward to our next real estate adventure,” the “West Wing” actor says.

Set on 3.4 acres of scenic grounds, the Lowes’ estate centers on a 10,000-square-foot main house that was designed by architect Don Nulty and built in 2009.

Also on the property are guest and pool houses, vegetable gardens and a swimming pool and spa.

A tennis court features two observation areas. Mature trees dot the grounds.

The main house is composed of 20 rooms, including a den/music room with a bar, family and commercial kitchens, an office, a screening room and a gym. The master suite has one of nine indoor fireplaces and a lavish bath for a total of six bedrooms and 9.5 bathrooms.

(Jim Bartsch / TNS)
(Jim Bartsch / TNS)

Sets of French doors lead outside, where expansive terraces and loggias create additional space for living and entertaining.

The manicured grounds, which include two outdoor fireplaces, fountain features and a koi pond, were done by landscape architect Mark Rios and feng shui consultant David Cho.

(Jim Bartsch / TNS)
(Jim Bartsch / TNS)

The guesthouse adds two bedrooms and a kitchenette.

Staff quarters, a bedroom and a full kitchen make up the pool house.

(Jim Bartsch / TNS)
(Jim Bartsch / TNS)

Lowe, 54, has scores of television and film credits, including prominent roles in “St. Elmo’s Fire,” “Parks and Recreation” and “Brothers & Sisters.”

He most recently starred as Dr. Ethan Willis on the medical drama “Code Black.”