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NEW YORK (AP) — Stocks that moved substantially or traded heavily Wednesday:

Morgan Stanley, up $1.48 to $46.62

The investment bank had a solid second quarter and its trading desks did better than its competitors.

McCormick & Co., down 56 cents to $164.85

The spice and seasonings maker agreed to buy the maker of French’s mustard for $4.2 billion.

Vertex Pharmaceuticals Inc., up $27.53 to $159.69

The drugmaker reported good results from studies of potential cystic fibrosis treatments.

Scripps Networks Interactive Inc., up $9.87 to $76.89

The Wall Street Journal said Scripps and Discovery Communications are in talks to combine.

IBM Corp., down $6.47 to $147.53

The technology and consulting company’s revenue fell short of analyst projections.

Hortonworks Inc., down $1.10 to $13.18

The business software company said President Rajnish Verma stepped down as it made management changes.

Northern Trust Corp., down $8.16 to $89.21

The bank and wealth management firm reported disappointing results for the second quarter.

CSX Corp., down $2.77 to $51.87

Investors weren’t impressed with the railroad’s second quarter results.