Washington (5-1, 3-0 Pac-12) at Stanford (6-0, 4-0) Time: 5 p.m., at Stanford Stadium TV: ABC-TV, Ch. 4. Radio: KJR 950 AM The line: Stanford...

Washington (5-1, 3-0 Pac-12) at Stanford (6-0, 4-0)

Time: 5 p.m., at Stanford Stadium

TV: ABC-TV, Ch. 4. Radio: KJR 950 AM

The line: Stanford by 20 ½.

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The setup: Washington, off to its best start in 10 years, gets a chance to prove itself against a Stanford team ranked No. 7 and riding a 14-game winning streak. The winner also stays undefeated in conference play and atop the Pac-12 North Division.

What to expect: Lots of points. The teams are ranked second (Stanford, at 45.8 points) and third (UW at 37) in the Pac-12 in scoring and are led by quarterbacks who rank among the top five in the nation in passing efficiency — Andrew Luck for Stanford and Keith Price for Washington.

Notes: UW leads the series 40-37-4, but Stanford has won the past three — its longest streak in the series since winning 10 in a row from 1967-76. Stanford’s 41-0 victory in Seattle last year was UW’s first home shutout defeat since 1976. … UW is ranked in both polls (No. 22 AP, No. 24 coaches), the first time it has been ranked in either poll since it was ranked one week in 2009 and the second time since 2003. … This is the first time UW has played a game in which both teams are ranked since facing Ohio State in the opener in 2003. … Former longtime UW assistant Randy Hart is the defensive-line coach at Stanford. … Price remains second in the country in touchdown passes with 21 behind Baylor’s Robert Griffin III, who has 22. … Stanford has outscored its foes 50-0 in the first quarter and 78-6 in the third. UW’s best quarter is the first, outscoring opponents 77-41. It has been outscored in the third quarter 40-34.

Key matchup: Stanford’s tight ends vs. Washington’s secondary. Stanford might throw to its tight ends more than any team in the country. Its three tight ends — Zach Ertz, Coby Fleener and Levine Toilolo — have combined for 44 catches for 837 yards and 12 TDs.

Injuries: UW — RB Deontae Cooper (knee), CB Adam Long (knee), DE Hau’oli Jamora (knee), RB Johri Fogerson (knee), S Taz Stevenson (knee), questionable; S James Sample (shoulder), probable. Stanford — LB Shayne Skov (knee), S Delano Howell (hand), CB Wayne Lyons (foot), out; WR Chris Owusu (concussion), probable.

Upset brewing? Many numbers favor the Cardinal, including the fact it has won all six games this year by at least 26 points. Stanford hasn’t scored fewer than 37 points in any game or allowed more than 19. But UW will have the best offense Stanford has faced so far, and the Cardinal is missing two key defenders — Skov, out for the year, and Howell, out this week.

Prediction: Stanford 38, Washington 27.

Bob Condotta