Michigan coach John Beilein left Happy Valley in a sour mood. Squandering a 15-point lead with 10 minutes to go against the last-place team...

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STATE COLLEGE, Pa. — Michigan coach John Beilein left Happy Valley in a sour mood.

Squandering a 15-point lead with 10 minutes to go against the last-place team in the Big Ten might not look very good on the fourth-ranked Wolverines’ postseason résumé.

Jermaine Marshall scored 25 points to lead Penn State’s furious comeback Wednesday night, and the Nittany Lions upset Michigan 84-78 for their first conference victory in more than a year.

“If you’re going to win a championship in this league, you really have to complete games and beat teams on the road, especially if they’re in the lower end of the division,” Beilein said. “Will it be deflating? Yeah, it will be.”

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Just another rough night for the league’s top teams in the rough-and-tumble Big Ten.

Top-ranked Indiana lost Tuesday at Minnesota to fall to 12-3 in conference play, so Michigan squandered a chance to move into a three-way tie for second with Michigan State and Wisconsin, a game back of the Hoosiers.

Tim Hardaway Jr. scored 19 points for the Wolverines (23-5, 10-5). Trey Burke had 18 points and six assists but also committed six turnovers.

Michigan had 15 turnovers in the game, six more than its season average.

And the Wolverines blew it down the stretch against a team that had lost 18 straight regular-season conference games dating to last season.

“They really tried to shut down Trey. We had some good shots, but not enough good ones,” Beilein said. “They slowed us up with their press a little bit, but we couldn’t stop them.”

It was Penn State’s first win over a top 5 team since defeating No. 5 North Carolina 82-74 in the second round of the 2001 NCAA tournament.

Penn State also got its first conference win since beating Iowa 69-64 on Feb. 16, 2012.

The Nittany Lions (9-18, 1-14) roared back from a 15-point deficit with 10:39 left behind the energetic play of Marshall. The junior guard scored 19 in the second half, including four threes that whipped fans into a frenzy. Sasa Borovnjak hit two free throws with 15 seconds left to seal it. When it was over, fans rushed the floor.

Other Top 10 men

At No. 5 Miami 76,

Virginia Tech 58

Shane Larkin had 22 points to lead the Hurricanes. Despite a slow start, Miami (23-4, 14-1 Atlantic Coast) never trailed and improved to 13-0 at home. Virginia Tech (12-16, 3-12) fell deeper into last place in the league.

No. 7 Georgetown 79,

at Connecticut 78 (2OT)

Otto Porter Jr.’s layup with 9.5 seconds left in the second overtime gave Georgetown a wild victory over Connecticut, the Hoyas’ 10th straight win. Porter scored 21 of his 22 points after halftime to help Georgetown (22-4, 12-3 Big East) stay in first place in the conference. DeAndre Daniels had 25 points and 10 rebounds for the Huskies (19-8, 9-6).

No. 10 Louisville 79,

at DePaul 58

Russ Smith scored 17 points and Peyton Siva from Franklin High School had 16 as the Cardinals (23-5, 11-4 Big East) won their fourth straight.

Brandon Young scored 22 points and Cleveland Melvin had 20 for the Blue Demons (11-17, 2-13), who have dropped three in a row and 12 of 13 overall.

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