MORE than five years after the tragic murder of her roommate, Seattle’s Amanda Knox has weathered two trials, nearly four years in prison, a Lifetime TV movie and legal bills well above $1 million.

What she doesn’t need is another stamp on her passport from Italy.

A ruling Tuesday by Italy’s Court of Cassation, equivalent to the Supreme Court, overturned Knox’s 2011 acquittal on charges of murdering Meredith Kercher in the house they shared in Perugia in November 2007. The ruling queues up a third trial.

If Italy seeks extradition of Knox, the U.S. government should look closely at the sad, bizarre course of this case and deny the request.

Her 2009 conviction was overturned in 2011 because of fundamental flaws in the evidence against her and her one-time Italian boyfriend, Raffaele Sollecito.

The prosecution’s theory — of a sex game involving Knox, Sollecito, Kercher and a fourth party gone brutally awry — was as ludicrous as it was flimsy.

Instead, evidence overwhelmingly pointed to the fourth party, Rudy Guede, who fled Italy after the murder before eventually being captured and pleading guilty.

The history of this case suggests a third trial would get the Kercher family no closer to relief. And it would undoubtedly expose Knox, who has returned to study at the University of Washington, to double jeopardy.

Strange quirks of Italian law allowed prosecutors to appeal the 2011 acquittal, and would allow Knox to be convicted in absentia in a third trial.

She undoubtedly will remain a target of international paparazzi, particularly after her memoir is published next month.

But she doesn’t deserve a forced return trip to Italy.